The difference is that apply lets you invoke the function with arguments as an array; call requires the parameters be listed explicitly. A useful mnemonic is " A for a rray and C for c omma."

See MDN's documentation on apply and call.

Pseudo syntax:

theFunction.apply(valueForThis, arrayOfArgs), arg1, arg2, ...)

There is also, as of ES6, the possibility to spread the array for use with the call function, you can see the compatibilities here.

Sample code:

function theFunction(name, profession) {
    console.log("My name is " + name + " and I am a " + profession +".");
theFunction("John", "fireman");
theFunction.apply(undefined, ["Susan", "school teacher"]);, "Claude", "mathematician");, ...["Matthew", "physicist"]); // used with the spread operator