You can use triple-quoted strings. When they're not a docstring (the first thing in a class/function/module), they are ignored.
''' This is a multiline comment. '''
(Make sure to indent the leading
''' appropriately to avoid an
However, Python's style guide, PEP8, favors using consecutive single-line comments, and this is also what you'll find in many projects. Text editors usually have a shortcut to do this easily.