Use the remove/erase idiom:

std::vector<int>& vec = myNumbers; // use shorter name
vec.erase(std::remove(vec.begin(), vec.end(), number_in), vec.end());

What happens is that remove compacts the elements that differ from the value to be removed (number_in) in the beginning of the vector and returns the iterator to the first element after that range. Then erase removes these elements (whose value is unspecified).