In general, anything that spans all the way across a screen is difficult for users to read. I'm not entirely sure if I understand the content you will have on this page, but assuming that what is shown would be all of the content, I would recommend making the profile box into a left sidebar and aligning the "about" text in the remaining 2/3rds (or so) of the screen, like this:
This would also allow more room for longer "about" info, since yours would clip longer text and force users to scroll.
If there would not be enough content to fill a layout like this, then maybe you could use your layout but in a skinnier page with wider side margins, which would make it look better proportionally. Of course, this would not be a solution if there are other pages to this site that would with the wider layout.